Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp106 | Adrenal and Neuroendocrine - Basic | ECE2019

Gene expression changes in visceral adipose tissue of Cushing syndrome.

Garcia-Eguren Guillermo , Gonzalez Mar , Blanco Enrique , Giro Oriol , Vidal Oscar , Carmona Francesc , Casals Gregori , Mora Mireia , Halperin Irene , diCroce Luciano , Hanzu Felicia A

Introduction: Visceral adipose tissue (VAT) is the key target tissue of glucocorticoids (GC) during active Cushing Syndrome (CS) and a metabolic tissue associated to insulin-resistance and an increased cardiometabolic risk. Till date there are no data regarding gene expression in VAT in CS and only few data about the mRNA in subcutaneous one. The aim of this study was to study the visceral VAT tissue transcriptional changes in ACTH-independent CS.Methods...